Learning objectives

This course has the aim to describe molecular mechanisms underlying pathological processes concerning essential cell and tissue functions and the consequent injury-induced tissue repair. The course addresses classical examples of molecular alterations affecting subcellular organelles and tissue interstitium. Additionally, complex alterations occurring at the organism level (aging, diabetes, steatosis) are described. In the context of cell damage, particular attention is given to alterations of signal transduction and cell transformation. This last pathology is addressed in the more general context of causes of tumor transformation, cancer cell biology and consequences of tumor growth at the organism level. Mechanisms of host defenses against pathogens and reaction to tissue injury are described in great details both in terms of cell involved and molecular mechanisms. Acute and chronic inflammation are addressed in the context of their causes, their cellular and molecular mechanisms and their interaction with the immune response.

Learning assessment procedures

Learning test contents : the test covers all the topics of the program

Methods of assessment : oral examination

Evaluation criteria

Evaluation methods
The ability of critical reasoning and exposition of the topics studied is evaluated

The objectives of the test have the aim to evaluate the knowledge of the molecular mechanisms underlying the pathological processes.

Votes expressed out of thirty