Teaching code

4S000089

Credits

4

Coordinatore

Hans Georg Kraft

Language

Italian

Moodle Seminars

The teaching is organized as follows:

Learning outcomes

The course provides knowledge of biology, biochemistry and genetics necessary for understanding the physiological and pathological processes related to health and disease of individuals in different stages of life. Biological and biochemical knowledge will contribute to the acquisition of skills that improve people's health and nursing care. At the end of the course students will possess basic knowledge of organic chemistry and biochemistry, the structure-function relationships of the main classes of biological macromolecules, their metabolic regulation and the energy transformations of biochemical processes; knowledge of cellular and genetic biology related to structural, functional and molecular characteristics of the cell; understanding of the applications of genomic knowledge to medicine. This knowledge will enable students to understand cellular processes common to all living organisms, the basic mechanisms that regulate metabolic activity, reproduction and cellular interactions and transmission of genetic diseases in humans. BIOCHEMISTRY: the Course provides: -Basic knowledge of organic chemistry preparatory for biochemistry. -Knowledge related to the structure-function relationships of the most important biological macromolecules and to their metabolic regulation. -Knowledge about the relation between the different biochemical processes and the regulation of the energy level associated to them. At the end of the course the student will acquired the proper scientific terms and notions in order to critically and autonomously evaluate the biochemical processes of life. APPLYED BIOLOGY: The course provides the cognitive basis for understanding the contribution of biological macromolecules in biological organization, in the functioning of the structures of living organisms and in the most relevant aspects of human biology. The course also aims to introduce the fundamental concepts of Genetics, the most common genetic diseases and their transmission modes. At the end of the course the student will be able to know and understand the fundamentals of biology also in relation to the health status of human population.

Program

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MM: BIOCHIMICA
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Wasser, Verteilung im Körper, Ionenkonzentrationen, Wasserabgabe und -aufnahme, Störungen im Wasserhaushalt, Dipolmoment, Dielektrizitätskonstante, Dipolmoment, Wasserstoffbrücken, Wasser als Lösungsmittel, Protolyse, chemische Reaktionen mit Wasser, Wärmekapazität, pH, Säure- Basenhaushalt, Carboanhydrasereaktion, biologische Puffersysteme, Proteine und Aminosäuren, Stereochemie von Aminosäuren, funktionelle Gruppen in AS, isoelektrischer Punkt von AS, essentielle AS, Primär- Sekundär- Teriär- und Quartärstruktur von Proteinen, Proteinabbau, Katabolismus von AS, Harnstoffzyklus. Kohlenhydrate, Polysaccharide, Aldosen, Ketosen, Glucose, glycosidische Bindungen, Mono- Disaccharide, Glucose Homeostase, Regulation durch Hormone (Insulin, Glucagon). Lipide, Aufbau, Funktionen, Triglyceride, Fettsäuren, Phospholipide, Lipidstoffwechsel. Nukleinsäuren, Aufbau von DNA und RNA, komplementäre Basenpaare, Replikation, DNA Reparatur, Transkription, Genregulation, Reifung der mRNA, Synthese von Ribosomen, tRNA, Biosynthese und Abbau von Nukleotiden, Gicht, Blut (Zellen und Plasmaproteine), Hämoglobinsynthese, Hämoglobinabbau. Enzyme, Inhibierung von Enzymen, enzymatische Messung der Glucosekonzentration, Glycolyse, Tricarbonsäurezyklus, Laktatmessung, alkoholische Gärung, Gluconeogenese, Ernährung, Funktionen der Organe im Verdauungstrakt, Vitamine und Spurenelemente, fettlösliche Vitamine, wasserlösliche Vitamine
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MM: BIOLOGIA APPLICATA
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da inserire --------------------------------------------------------

Bibliography

Examination Methods

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MM: BIOCHIMICA
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written exam using multiple choice items
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MM: BIOLOGIA APPLICATA
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written test with multiple choice items