Studying at the University of Verona

Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.

Study Plan

This information is intended exclusively for students already enrolled in this course.
If you are a new student interested in enrolling, you can find information about the course of study on the course page:

Laurea magistrale in Molecular and Medical Biotechnology - Enrollment from 2025/2026

The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.

2° Year  activated in the A.Y. 2022/2023

ModulesCreditsTAFSSD
Training
2
F
-
Final exam
40
E
-
activated in the A.Y. 2022/2023
ModulesCreditsTAFSSD
Training
2
F
-
Final exam
40
E
-
Modules Credits TAF SSD
Between the years: 1°- 2°
2 courses among the following ("BIOTECHNOLOGY IN NEUROSCIENCE" AND "CLINICAL PROTEOMICS" 1ST AND 2ND YEAR; THE OTHER COURSES 2ND YEAR ONLY)

Legend | Type of training activity (TTA)

TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.




S Placements in companies, public or private institutions and professional associations

Teaching code

4S009682

Credits

6

Language

English en

Scientific Disciplinary Sector (SSD)

BIO/10 - BIOCHEMISTRY

The teaching is organized as follows:

Teoria

Credits

5

Period

Secondo semestre

Academic staff

Alessandra Astegno

Laboratorio [1° turno]

Credits

1

Period

Secondo semestre

Academic staff

Alessandra Astegno

Laboratorio [2° turno]

Credits

1

Period

Secondo semestre

Academic staff

Alessandra Astegno

Laboratorio [3° turno]

Credits

1

Period

Secondo semestre

Academic staff

Alessandra Astegno

Learning outcomes

The course introduces students to enzymology and the application of enzymes in medical biotechnology and medicine. The students will acquire advanced knowledge on enzymes mechanisms and regulation, technology of enzyme production, new biotechnological strategies in engineering of enzymes aimed to their improved use in the medical and pharmaceutical fields. The main part of the course will be focused on selected applications of enzymes in biomedicine, diagnostics and therapy.

Program

Theory
• Introduction to enzymes and enzyme kinetics
• Production of recombinant enzymes/proteins
• Protein engineering: directed and rationale evolution for production of new enzymes
• Enzyme therapy in metabolic disorders:
1. Lysosomal storage diseases
2. Disorders of amino acid metabolism
3. Disorders of nucleotide metabolism
• Enzymes in cancer therapy
• Fibrinolytic enzymes for thrombolytic therapy
• Enzymes in diagnosis and diagnostics

Laboratory
Session1: purification of recombinant wild type cystathionine beta synthase and its pathogenic variants via affinity chromatography. Analysis of the affinity purified enzyme samples by SDS-PAGE.
Session2: characterization of wild type and pathogenic mutants using kinetic and spectrophotometric methods (cofactor content of the enzyme and steady-state kinetic properties)

Examination Methods

Written:
- Multiple choice questions
- Open-ended questions

Students with disabilities or specific learning disorders (SLD), who intend to request the adaptation of the exam, must follow the instructions given HERE