Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Study Plan
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea magistrale in Molecular and Medical Biotechnology - Enrollment from 2025/2026The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.
1° Year
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2 courses among the following3 courses among the following1 course among the following1 course among the following2° Year activated in the A.Y. 2022/2023
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| Modules | Credits | TAF | SSD |
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2 courses among the following3 courses among the following1 course among the following1 course among the following| Modules | Credits | TAF | SSD |
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| Modules | Credits | TAF | SSD |
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2 courses among the following ("BIOTECHNOLOGY IN NEUROSCIENCE" AND "CLINICAL PROTEOMICS" 1ST AND 2ND YEAR; THE OTHER COURSES 2ND YEAR ONLY)Legend | Type of training activity (TTA)
TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.
Farming molecolare (2022/2023)
Teaching code
4S003677
Teacher
Coordinator
Credits
6
Language
English
Scientific Disciplinary Sector (SSD)
BIO/15 - PHARMACEUTICAL BIOLOGY
Period
Semester 1 dal Oct 3, 2022 al Jan 27, 2023.
Learning objectives
The course aims to give the students notions of the use of recombinant systems for the production of biopharmaceuticals. In particular, the course will be focused on the biomolecular techniques used for the expression of recombinant proteins in prokaryotic and eukaryotic systems and the downstream processing and purification for their large-scale production. The different platforms used for the recombinant expression will be studied and compared. The different US and EU normative procedures for biopharmaceutical commercialization will be evaluated and compared. Specific examples of biopharmaceutical produced in recombinant systems and their therapeutic applications like for vaccines and antibodies will be discussed and studied.
Prerequisites and basic notions
Basic knowledge in molecular biology, biochemistry and immunology
Program
General introduction to the concept of Molecular farming
Definition of a biopharmaceuticals and drugs
Route for biopharmaceuticals approval. The Clinical Trials and the Regulatory pathways
Biosimilars and Bioequivalence
Platforms for the heterologous production of recombinant proteins with a focus on the relative upstream processes
The main categories of biopharmaceuticals: Antibodies, Vaccines and Hormones
Passive immunization: the antibodies
Heterologous expression of antibodies Active immunization: the vaccines Heterologous production of vaccines Immunogenicity
Post-translational modifications
Immunological tolerance and oral tolerance
The downstream processing
Production of peptides and their applications Techno-economic analysis for the production of antibodies
Patent, Clinical Trials and Description of a Biopharmaceutical
Didactic methods
The teaching will be performed in presence. Lectures of October and November will be accessible also via streaming and the zoom link will be reported in the moodle section
Learning assessment procedures
Written test (optional) and Oral Test.
Evaluation criteria
The student will be evaluated for her/his knowledge of the topic of the course and for the ability to use them to a practical example of production of a biopharmaceutical
Criteria for the composition of the final grade
The final score will be the sum of the score of the oral exam (27/27) and of the written assay (3/3)
Exam language
Inglese/italiano
