Teaching code

4S00179

Academic staff

Stefano Ugel, Francesco De Sanctis

Coordinator

Stefano Ugel

Credits

9

Language

Italian

Scientific Disciplinary Sector (SSD)

MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY

Period

2° semestre dal Feb 19, 2024 al May 31, 2024.

Location

VERONA

Courses Single

Not Authorized

Lessons timetable Moodle Seminars 0

Learning objectives

Aims of the Immunology course are: acquisition of the knowledge of the fundamental biological and physiological mechanisms regulating the function of the immune system in the protection from diseases, and of the immune system pathology, with particular attention to hypersensitivity, autoimmunity and immunodeficiency; acquisition of the ability to consider the function of the immune system both in health and in disease status and of the bases of the most common laboratory immune techniques in order to become able to understand the results of any laboratory analysis based on immunological techniques; knowledge of the immune responses against infections, of both the congenital and the acquired disfunctions of the immune system, of the hypersensibility reactions and of the main autoimmune as well as lymphoproliferative diseases; knowledge of the immune strategies applied to the therapy of allergies and immunodeficiencies; knowledge of the general principles of vaccination therapy and immune suppression; kowledge of tumor immunology and immunology of transplantation.

Prerequisites and basic notions

Preliminary knowledge of anatomy, biology and histology

Program

Innate and acquired immunity. Anatomy, cytology and biochemistry of the immune system: lymphoid organs, cells (lymphocytes, dendritic cells, macrophages, granulocytes), molecules (Immunoglobulins, T cell receptor, MHC molecules, costimulatory molecules). Cellular receptors, Toll Like Receptors (TLR). Antigen processing and presentation. Cell-mediated and humoral immune response. The complement system. Cytokines, chemokines and cellular cooperation. Defense against infections. Immunological tolerance. Hypersensitivity reactions. Autoimmune Diseases. Immunodeficiency. Immunity and tumors. Principles of Immunotherapy. Immunohematology, Transplant Immunology.

Bibliography

Didactic methods

Lectures and additional activities in E-learning mode (study of scientific articles and in-depth lessons on specific topics of the course). Attendance is 75% mandatory

Learning assessment procedures

Written test, with multiple choice questions on the entire teaching programme. If the grade of the written test is rejected (grade higher than 18/30) it will be possible to take the oral test (on a date to be agreed with the teacher; in this case the grade obtained in the written test will not be considered and a new exam will be taken on whose outcome can be positive or negative). Alternatively, you can repeat the writing at the next exam.

Evaluation criteria

The written exam is based on multiple choice questions. Each correct answer is worth 2 points. Each wrong answer is worth -1 point. Each answer not given is worth 0 points. The oral exam includes an interview with questions aimed at verifying the actual achievement of the indicated learning objectives. The evaluation of the exam test in thirtieths

Criteria for the composition of the final grade

Evaluation of the exam out of thirty

Exam language

Italiano