Learning objectives

Knowledge of the basics of Microbiology and Clinical Microbiology

Prerequisites and basic notions

Knowledge of basic biology and cytology

Program

Introduction to medical microbiology, Commensal and pathogenic microbial flora in humans. General information on laboratory diagnostics, Microscopy and in vitro cultures, Molecular and serological diagnostics in Microbiology. General information on the immune response, Innate and acquired responses, Vaccines and sera. Sterilization, disinfection and antisepsis. Bacteriology Structure, metabolism, replication and genetics of bacteria. Mechanisms of pathogenesis of bacterial diseases. Antibacterial drugs, mechanisms of resistance to antibacterial drugs. The main bacteria pathogenic to humans: Staphylococci, Streptococci, Enterococci, Bacillus anthracis, Listeria monocytogenes, Corynebacteria, Mycobacteria, Neisseria, Hemophili, Enterobacteriaceae, Vibrio, Campylobacter, Helicobacter, Pseudomonas, Acinetobacter, Bartonella, Bordetella, Brucella, Legionella, Clostridia, Actinomycetes, Spirochetes, Mycoplasmas, Rickettsiae, Orientia, Ehrlichia, Coxiella, Chlamydiae and other minor bacteria. Virology Classification, structure and replication of viruses, Viral pathogenesis, viruses pathogenic to humans, Diagnosis of viral infection, Antiviral drugs and control of infection. Main pathogenic viruses for humans: Poxvirus, Adenovirus, Papovavirus, Herpesvirus, Parvovirus, Picornavirus, Coronavirus and Norovirus, Paramyxovirus, Orthomyxovirus, Rhabdovirus, Filovirus, Reovirus, Togavirus, Flavivirus, Bunyaviridae and Arenaviridae, Retrovirus, Hepatitis viruses. Fungi Classification, structure and replication of fungi, Pathogenesis of fungal diseases, Pathogenic fungi for humans, mycotoxins and mycotoxicoses. Diagnosis of fungal infection, Antifungal drugs. Superficial, cutaneous and subcutaneous mycoses, Systemic mycoses caused by dimorphic fungi, Opportunistic mycoses. Parasitology Classification, structure and replication of parasites, Pathogenesis of parasitic diseases, Protozoa and helminths pathogenic for humans, Diagnosis of parasitic infection, Antiprotozoan and anthelmintic drugs. Giardia intestinalis, Amoebae, Trichomonas vaginalis, Cryptosporidium spp, Plasmodium spp, Toxoplasma gondii, Leishmaniae, Trypanosomes, Helminths pathogenic to humans (Nematodes, Trematodes, Cestodes). Prions

Bibliography

Didactic methods

Presentation of topics through frontal lessons

Learning assessment procedures

Oral exam aimed at ascertaining the actual achievement of the learning objectives

Evaluation criteria

Assessment of knowledge of the program topics.

Criteria for the composition of the final grade

Overall result of the oral exam expressed in thirtieths

Exam language

Italiano

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