Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Study Plan
The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.
1° Year
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2° Year It will be activated in the A.Y. 2025/2026
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3° Year It will be activated in the A.Y. 2026/2027
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Legend | Type of training activity (TTA)
TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.
Radiobiology and Radiation Protection - Applied biology and radiobiology (2024/2025)
Teaching code
4S001359
Teacher
Credits
2
Language
Italian
Scientific Disciplinary Sector (SSD)
BIO/13 - EXPERIMENTAL BIOLOGY
Period
1 SEMESTRE PROFESSIONI SANITARIE dal Oct 1, 2024 al Dec 20, 2024.
Courses Single
Not Authorized
To show the organization of the course that includes this module, follow this link: Course organization
Program
At the end of the course the student must know the following topics:
Foundations of modern biological thought, appearance of the first organisms on Earth
Prokaryotes: general characteristics, evolution from prokaryotes to eukaryotes
The eukaryotic cell: general characteristics, evolution of multicellular organisms
The nucleus, chromosomes, cell division: mitosis
Sexual reproduction and meiosis. Gametogenesis in humans
Normal and pathological human karyotype, sex chromosomes, gene dosage compensation
Molecular basis of hereditary information. DNA. Structure and replication
Flow and control of information: transcription, translation, protein maturation
Spontaneous and induced mutations, chemical mutagens, mutagenesis tests
Somatic mutations and cancer. Physical mutagens / Radiobiology
Non-ionizing radiation (UV): cell impact, DNA damage repair systems
Ionizing radiation (IR): X-rays, alpha, beta, gamma
RBE (relative biological effectiveness) is related to the LET value (definition)
The birth of radiobiology: the first laboratory experiments: Bergonie and Tribondeau, Müller
Cell cultures and survival curves
Radiosensitivity of different cell types
DNA damage: direct (double-strand breakage, chromosome aberrations) and indirect (radiolysis of water, production of free radicals, point mutations)
Oxygen effects (OER)
Methodological approaches for the detection of DNA damage: the comet assay, karyotype analysis
Immediate and long-term effects: definition
Long-term effects: tumorigenesis (some mention to the data after the Chernobyl) and reproductive risk.
Ability of the organisms to repair DNA damage and sensitivity / resistance to IR, two extreme examples: Ataxia telangiectasia and Deinococcus radiodurans
Genetic transmission of characteristics, laws of Mendel, dominance and recessive
Human genetics: the blood groups
Analysis of family trees. Examples of genetic diseases with autosomal dominant, autosomal recessive, X-linked.
Bibliography
Didactic methods
The teacher will use frontal lessons
Learning assessment procedures
The assessment of the learning outcomes includes a written test aimed at ascertaining the knowledge of the topics in the program. Questions are formulated as multiple choice and open-ended questions. The questions require knowledge of scientific terminology in biology, the ability to interpret family trees, the ability to link knowledge of biology and radiobiology, the ability to describe and exemplify biological structures.
Evaluation criteria
The evaluation will be expressed out of thirty and will be considered positive if greater than or equal to 18/30.
Exam language
Italiano
