Teaching code

4S000469

Teacher

Patrizia Scapini

Credits

2

Also offered in courses:

• Phisiology and principles of genetics - PATOLOGIA GENERALE E IMMUNOLOGIA of the course Bachelors' degree in Health Assistance

Language

Italian

Scientific Disciplinary Sector (SSD)

MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY

Period

1 SEMESTRE PROFESSIONI SANITARIE dal Oct 3, 2022 al Dec 23, 2022.

Lessons timetable Moodle Seminars 0

To show the organization of the course that includes this module, follow this link:  Course organization

Learning objectives

The student must acquire knowledge of the mechanisms of cellular and molecular damage and of the pathogenetic processes and mechanisms of reaction to restore health. The main training objectives are:
• understanding of the mechanisms of cellular and molecular damage;
• learn about reactions to biological damage which are crucial in the process of healing/repair or pathology, with an emphasis on mechanisms of immunity, inflammation, wound healing and chronic biological processes;
• gain knowledge of scientific terms and language that are used in medical practice in order to effectively communicate with other health care professionals.

Program

I. Introduction:
- general concepts
- the pathological process as an alteration of homeostasis
- adaptation, compensation and responsiveness
- pathogenesis
- etiology
II. Cellular Pathology:
-cell death: necrosis and apoptosis
- pathogenetic processes implicated in cellular damage
III. Natural immunity and acquired immunity:
- innate immune cells
- adaptive immune cells
IV. Tissue responses to cell damage:
- acute inflammation: changes in flow and vascular permeability;
- inflammatory exudates (types, composition, localization);
- mechanisms controlling phagocyte migration to the inflammatory sites
- effector functions of phagocytes: oxygen-dependent and oxygen-independent bactericidal mechanisms, phagocytosis
V. Mediators of acute inflammation: plasma-derived mediators and cell-derived mediators
- coagulation system, complement system, vasoactive amines
- cytokines
VI. Evolution of the acute inflammatory response:
-tissue repair, regeneration and fibrosis
-chronic inflammation: chronic systemic diseases that affect the joints and connective tissues
VII. Neoplasms

Bibliography

Didactic methods

The lessons will be held in person with the help of powerpoint presentations.
For students who will find themselves in isolation due to positivity to Covid, didactic material to recover the contents of the lesson will be made accessible on moodle. The communication of isolation due to Covid infection must be made by the student to the individual teacher using the self-certification form available on the coronavirus Student Info web page. By clicking on “Lessons, exams and graduation exams - request form for date change / supplementary teaching material.
In addition, students in particular situations of fragility, unable to attend classes due to disability conditions or particularly disabling learning disorders, are invited to contact the "Inclusion and Accessibility Service", which will assess the actual impossibility of attendance on a case-by-case basis and will agree on the support modalities with the teachers .

Learning assessment procedures

The evaluation is performed as a written test within the exam of PATHOLOGY (visit also the assessment methods and criteria reported on the general web page of the course).
The exam will focus on the topics covered in class and listed in the course program.

Evaluation criteria

The assignment of General Pathology consists of a written test with 21 multiple choice questions.
The evaluation criteria are the following: 1,5 points for correct answers; 0,75 points for partially correct answers; 0 points for missing/wrong answers.
A positive evaluation is reached when the student achieves a minimal overall grade of 18 points.

Exam language

Italiano