Training and Research
PhD Programme Courses/classes
This page shows the PhD course's training activities for the academic year 2024/2025. Further activities will be added during the year. Please check regularly for updates!
Gut Microbiota: From the Forgotten Organ to a Potential Key Player in Pathology
Credits: 0.5
Language: inglese
Teacher: Elena Zenaro
Cancer immunotherapy in cancer
Credits: 0.5
Language: Inglese
Teacher: Francesco De Sanctis
Genome regulation by long non coding RNAs
Credits: 0.5
Language: English
Teacher: Barbara Mariotti
Endothelial cells
Credits: 0.5
Language: Italian
Teacher: Carlo Laudanna
Kidney cancers: anatomo clinical approaches
Credits: 0.5
Language: Inglese
Teacher: Guido Martignoni
Training the innate immunity
Credits: 0.5
Language: english
Teacher: Flavia Bazzoni
Dalla Patologia alla Genomica e ritorno
Credits: 0.5
Language: Inglese
Teacher: Andrea Mafficini
Lung cancer as the paradigm of precision medicine
Credits: 0.5
Language: English
Teacher: Sara Pilotto
Approaches to study intra-tumor heterogeneity
Credits: 0.5
Language: Inglese
Teacher: Vincenzo Corbo
Radiomics in Oncology
Credits: 0.5
Language: inglese
Teacher: Riccardo De Robertis Lombardi
Advanced microscopy for the study of tissue pathology and cellular dysfunction
Credits: 0.5
Language: Italian
Teacher: Enrica Caterina Pietronigro
Tissue resident memory CD8 T cells
Credits: 0.5
Language: English
Teacher: Eleonora Terrabuio
Citometria a flusso: principi, pratica e tecniche avanzate
Credits: 0.5
Language: English
Teacher: Andrea Mafficini
Precision Functional Genomics in Cancer
Credits: 0.5
Language: Inglese
Teacher: Vincenzo Corbo
Modulazione della resistenza al trattamento nell'adenocarcinoma pancreatico duttale agendo sul microambiente tumorale
Credits: 0.5
Language: English
Teacher: Davide Melisi
Myeloid cells induced by cancer
Credits: 0.5
Language: INGLESE
Teacher: Stefano Ugel
Precision Medicine in Pancreatic Cancer
Credits: 0.5
Language: English
Teacher: Claudio Luchini
slan+-monocytes in health and disease
Credits: 0.5
Language: English
Teacher: Marco Antonio Cassatella
The effects and mechanisms of a lifestyle-based approach on cancer-related outcomes
Credits: 0.5
Language: English
Teacher: Sara Pilotto
Ruolo dei neutrofili nella neurodegenerazione
Credits: 0.5
Language: inglese
Teacher: Gabriela Constantin
Le risposte antivirali del sistema immunitario
Credits: 0.5
Language: English
Teacher: Nicola Tamassia
Neutrophil heterogeneity in health and diseases
Credits: 0.5
Language: Italian
Teacher: Patrizia Scapini
Mechanisms of cancer cells adaptation to microenvironmental challenges
Credits: 0.8
Language: Inglese
Teacher: Vincenzo Corbo
Immunità meningeale durante condizioni fisiologiche e patologiche
Credits: 1
Language: inglese
Teacher: Gabriela Constantin, Barbara Rossi
Progettazione e conduzione di studi clinici di fase 1 per lo sviluppo di nuove terapie sperimentali contro il cancro
Credits: 0.5
Language: English
Teacher: Davide Melisi
T cell activation: the role of CD1
Credits: 0.5
Language: Inglese
Teacher: Barbara Rossi
Biomarcatori per l'implementazione dell'oncologia di precisione
Credits: 0.5
Language: English
Teacher: Michele Milella
Fluorescent in situ hybridization analysis (FISH) on cancer
Credits: 0.5
Language: italiano
Teacher: Matteo Brunelli
Alterazioni molecolari nei gliomi
Credits: 0.5
Language: inglese
Teacher: Valeria Barresi
Applicazione della tecnologia degli organoidi in fibrosi cistica
Credits: 0.5
Language: english
Teacher: Claudio Sorio
Radiomics in Oncology
Credits: 0.5
Language: Italian
Teacher: Riccardo De Robertis Lombardi
Twist and turn on the path of precision oncology in routine clinical practice
Credits: 0.5
Language: English
Teacher: Michele Milella
Approaches to study intra-tumor heterogeneity (2024/2025)
Teacher
Referent
Credits
0.5
Language
Inglese
Class attendance
Free Choice
Location
VERONA
Learning objectives
The course is intended to provide students with the basic notions relating to the nature and significance (both biological and clinical) of intratumor heterogeneity.
Prerequisites and basic notions
None
Program
A clear distinction will be made between genetic (point mutations, copy number variations) and epigenetic (different transcriptional states and/or local or general chromatin accessibility) differences. Subsequently, the main technologies and methodologies for the study of genetic heterogeneity (e.g., bulk sequencing, comparative lesion sequencing) will be presented together with statistical approaches for inference of cancer clonal structure and phylogenetic relationships between samples from the same patient (mainly on the basis of "variant allele frequency"). Specific examples from recent high-profile literature will introduce students to the main theories on the temporal evolution of solid tumors that explain intratumoral heterogeneity. Finally, new methodologies of single-cell DNA sequencing and spatial genomics will be mentioned.
Didactic methods
Frontal lecture with slide support. Students will be provided with bibliographical references
Learning assessment procedures
No verification
Assessment
No rating
Criteria for the composition of the final grade
No final vote
Scheduled Lessons
| When | Classroom | Teacher | topics |
|---|---|---|---|
|
Friday 21 February 2025 14:00 - 16:00 Duration: 2:00 AM |
auletta didattica sezione anatomia patologica | Vincenzo Corbo | The course is designed to provide students with fundamental knowledge regarding the nature and significance (both biological and clinical) of intratumoral heterogeneity. A clear distinction will be made between genetic differences (e.g., point mutations, copy number variations) and epigenetic differences (e.g., different transcriptional states and/or local or global chromatin accessibility). Subsequently, the main technologies and methodologies for studying genetic heterogeneity (e.g., bulk sequencing, comparative lesion sequencing) will be presented, along with statistical approaches for inferring the clonal structure of cancer and phylogenetic relationships between samples from the same patient (primarily based on "variant allele frequency"). Using specific examples from high-profile recent literature, students will be introduced to the main theories on the temporal evolution of solid tumors that explain intratumoral heterogeneity. Finally, new methodologies such as single-cell DNA sequencing and spatial genomics will be briefly discussed. |
