Studying at the University of Verona

Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.

Type D and Type F activities

This information is intended exclusively for students already enrolled in this course.
If you are a new student interested in enrolling, you can find information about the course of study on the course page:

Laurea magistrale in Molecular and Medical Biotechnology - Enrollment from 2025/2026

Type D learning activities are the student's choice, type F activities are additional knowledge useful for job placement (internships, transversal skills, project works, etc.). According to the Teaching Regulations of the Course, some activities can be chosen and entered independently in the booklet, others must be approved by a special committee to verify their consistency with the study plan. Type D or F learning activities can be covered by the following activities.

1. Modules taught at the University of Verona

Include the modules listed below and/or in the Course Catalogue (which can also be filtered by language of delivery via Advanced Search).

Booklet entry mode: if the teaching is included among those listed below, the student can enter it independently during the period in which the curriculum is open; otherwise, the student must make a request to the Secretariat, sending the form to carriere.scienze@ateneo.univr.it during the period indicated.

2. CLA certificate or language equivalency

In addition to those required by the curriculum/study plan, the following are recognized for those matriculated from A.Y. 2021/2022:

  • English language: 3 CFUs are recognized for each level of proficiency above that required by the course of study (if not already recognized in the previous course of study).
  • Other languages and Italian for foreigners: 3 CFUs are recognized for each proficiency level starting from A2 (if not already recognized in the previous study cycle).

These CFUs will be recognized, up to a maximum of 6 CFUs in total, of type F if the study plan allows it, or of type D. Additional elective credits for language knowledge may be recognized only if consistent with the student's educational project and if adequately justified.

Those enrolled until A.Y. 2020/2021 should consult the information found here.

Method of inclusion in the booklet: request the certificate or equivalency from CLA and send it to the Student Secretariat - Careers for the inclusion of the exam in the career, by email: carriere.scienze@ateneo.univr.it

3. Transversal skills

Discover the training paths promoted by the University's TALC - Teaching and learning center intended for students regularly enrolled in the academic year of course delivery https://talc.univr.it/it/competenze-trasversali

Mode of inclusion in the booklet: the teaching is not expected to be included in the curriculum. Only upon obtaining the Open Badge will the booklet CFUs be automatically validated. The registration of CFUs in career is not instantaneous, but there will be some technical time to wait.  

4. CONTAMINATION LAB 

The Contamination Lab Verona (CLab Verona) is an experiential course with modules on innovation and enterprise culture that offers the opportunity to work in teams with students from all areas to solve challenges set by companies and organisations.  

Upon completion of a CLab, students will be entitled to receive 6 CFU (D- or F-type credits).  

Find out more:  https://www.univr.it/clabverona 

PLEASE NOTE: In order to be admitted to any teaching activities, including those of your choice, you must be enrolled in the academic year in which the activities in question are offered. Students who are about to graduate in the December and April sessions are therefore advised NOT to undertake extracurricular activities in the new academic year in which they are not enrolled, as these graduation sessions are valid for students enrolled in the previous academic year. Therefore, students who undertake an activity in an academic year in which they are not enrolled will not be granted CFU credits.  

5. Internship/internship period

In addition to the CFUs stipulated in the curriculum/study plan (check carefully what is indicated on the Teaching Regulations): here information on how to activate the internship. 

Check in the regulations which activities can be Type D and which can be Type F.

Modules and other activities that can be entered independently in the booklet

Academic year:
Semester 2 From 3/4/24 To 6/14/24
years Modules TAF Teacher
Python programming language D Carlo Combi (Coordinator)

Teaching code

4S003666

Credits

6

Language

English en

Scientific Disciplinary Sector (SSD)

BIO/18 - GENETICS

Courses Single

Authorized

The teaching is organized as follows:

Teoria

Credits

5

Period

Semester 1

Academic staff

Massimo Delledonne

Laboratorio [1° turno]

Credits

1

Period

Semester 1

Academic staff

Massimo Delledonne

Laboratorio [2° turno]

Credits

1

Period

Semester 1

Academic staff

Marzia Rossato

Laboratorio [3° turno]

Credits

1

Period

Semester 1

Academic staff

Marzia Rossato

Learning objectives

Scope of the course is to provide the most important concepts of clinical genomics, describing the structure and the function of the human genome as well as the most advanced approaches for its clinical interpretation A key point of the course is the detailed description of the human genome sequencing and annotation approaches carried out by the international public consortium, and by the private (Celera) initiative. The reference genome is indeed a fundamental component of nowadays human resequencing in precision medicine, and describes many key points about the structure and the function of the human genome. Then, the course will focus on the technologies of next generation sequencing and their use in detecting single nucleotide variants as well as large genomic structural variations At the completion of the course the students will be able to properly analyze and interpret a whole human genome.

Prerequisites and basic notions

A solid background in genetics and molecular biology is required

Program

SEQUENCING TECHNOLOGIES
• Sanger
• Second generation sequencing technologies
• Third generation sequencing technologies
• Whole genome sequencing
• Targeted Capture Methods for exome and gene panels
• RNA Sequencing and Methylome Analysis
THE HUMAN GENOME
The human genome sequencing consortium project
• CG content and CpG islands
• Repetitive sequences in the human genome
• Segmental duplications
• Gene content
The human genome sequencing project by Celera
• Shot gun sequencing and hybrid assembly
• Gene prediction and annotation
• SNPs in the human genome
THE ENCODE PROJECT
• Transcribed and protein-coding regions (GENCODE)
• Open chromatin
• Histone mark enrichment
• Transcription factor binding
• Gene expression
• Transcription start site (TSS) activity profiles
• RNA binding protein occupancy
• DNA methylation
• Three dimensional chromatin interactions
• Topologically associating domains (TADs)
THE HUMAN EPIGENOME
• Epigenetics and epigenomics
• DNA packaging and chromatin modification
• DNA methylation
• Histone modification
• Chromosome territories and transcriptional factories
• Topologically Associated Domains (TADs) and insulators
• The epigenetic basis of gene imprinting
• Epigenetic control of cellular differentiation
• Reprogramming the epigenome
CLINICAL GENOMICS (Bioinformatics)
Base Calling, Read Mapping and Coverage Analysis
Clinical Genome Analysis
• Detection of Single Nucleotide Variant
• Detection of Insertions and Deletions (Indels)
• Detection of Translocations
• Detection of Copy Number Variants

Bibliography

Visualizza la bibliografia con Leganto, strumento che il Sistema Bibliotecario mette a disposizione per recuperare i testi in programma d'esame in modo semplice e innovativo.

Didactic methods

Frontal lessons with video and slides support. Laboratory exercises

Learning assessment procedures

Written, open questions

Students with disabilities or specific learning disorders (SLD), who intend to request the adaptation of the exam, must follow the instructions given HERE

Evaluation criteria

Each answer is evaluated globally. Details are appreciated, although the evaluation is mainly focused on the overall description of the argument

Criteria for the composition of the final grade

11 questions, up to 3 points per question. When the final score is > 30, the grade is 30 Lode

Exam language

Questions are in English. Answers can be in English or Italian