Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Type D and Type F activities
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea magistrale in Molecular and Medical Biotechnology - Enrollment from 2025/2026Type D learning activities are the student's choice, type F activities are additional knowledge useful for job placement (internships, transversal skills, project works, etc.). According to the Teaching Regulations of the Course, some activities can be chosen and entered independently in the booklet, others must be approved by a special committee to verify their consistency with the study plan. Type D or F learning activities can be covered by the following activities.
1. Modules taught at the University of Verona
Include the modules listed below and/or in the Course Catalogue (which can also be filtered by language of delivery via Advanced Search).
Booklet entry mode: if the teaching is included among those listed below, the student can enter it independently during the period in which the curriculum is open; otherwise, the student must make a request to the Secretariat, sending the form to carriere.scienze@ateneo.univr.it during the period indicated.
2. CLA certificate or language equivalency
In addition to those required by the curriculum/study plan, the following are recognized for those matriculated from A.Y. 2021/2022:
- English language: 3 CFUs are recognized for each level of proficiency above that required by the course of study (if not already recognized in the previous course of study).
- Other languages and Italian for foreigners: 3 CFUs are recognized for each proficiency level starting from A2 (if not already recognized in the previous study cycle).
These CFUs will be recognized, up to a maximum of 6 CFUs in total, of type F if the study plan allows it, or of type D. Additional elective credits for language knowledge may be recognized only if consistent with the student's educational project and if adequately justified.
Those enrolled until A.Y. 2020/2021 should consult the information found here.
Method of inclusion in the booklet: request the certificate or equivalency from CLA and send it to the Student Secretariat - Careers for the inclusion of the exam in the career, by email: carriere.scienze@ateneo.univr.it
3. Transversal skills
Discover the training paths promoted by the University's TALC - Teaching and learning center intended for students regularly enrolled in the academic year of course delivery https://talc.univr.it/it/competenze-trasversali
Mode of inclusion in the booklet: the teaching is not expected to be included in the curriculum. Only upon obtaining the Open Badge will the booklet CFUs be automatically validated. The registration of CFUs in career is not instantaneous, but there will be some technical time to wait.
4. Contamination lab
The Contamination Lab Verona (CLab Verona) is an experiential course with modules on innovation and enterprise culture that offers the opportunity to work in teams with students from all areas to solve challenges set by companies and organisations.
Upon completion of a CLab, students will be entitled to receive 6 CFU (D- or F-type credits).
Find out more: https://www.univr.it/clabverona
PLEASE NOTE: In order to be admitted to any teaching activities, including those of your choice, you must be enrolled in the academic year in which the activities in question are offered. Students who are about to graduate in the December and April sessions are therefore advised NOT to undertake extracurricular activities in the new academic year in which they are not enrolled, as these graduation sessions are valid for students enrolled in the previous academic year. Therefore, students who undertake an activity in an academic year in which they are not enrolled will not be granted CFU credits.
5. Internship/internship period
In addition to the CFUs stipulated in the curriculum/study plan (check carefully what is indicated on the Teaching Regulations) here you can find information on how to activate the internship.
Check in the regulations which activities can be Type D and which can be Type F.
Please also note that for traineeships activated after 1 October 2024, it will be possible to recognise excess hours in terms of type D credits, limited only to traineeship experiences carried out at host organisations outside the University.
| years | Modules | TAF | Teacher |
|---|---|---|---|
| 2° | Python programming language [English edition] | D |
Carlo Combi
(Coordinator)
|
| years | Modules | TAF | Teacher |
|---|---|---|---|
| 2° | Python programming language [Edizione in italiano] | D |
Carlo Combi
(Coordinator)
|
Medical genetics and pharmacogenomics (2024/2025)
Teaching code
4S003672
Academic staff
Coordinator
Credits
6
Language
English
Scientific Disciplinary Sector (SSD)
MED/03 - MEDICAL GENETICS
Period
Semester 2 dal Mar 3, 2025 al Jun 13, 2025.
Courses Single
Authorized
Learning objectives
The course provides the principles of medical genetics and pharmacogenomics. It aims to show when and how the genetic factor, defined at different resolution levels (from chromosomes to single nucleotide) plays a role in the variability of Mendelian and complex diseases, and of the variability of drug-response. The course aims to provide students with the tools to be able to evaluate critically and independently the results of scientific research in the field of medical genetics and pharmacogenomics.
Prerequisites and basic notions
To successfully follow the course, basic knowledge of the fundamentals of biology and formal genetics is required.
Program
Human chomosomes, standard karyotype and numerical and structural chromosomal abnormalities. Chromosomal polymorphisms and CNV.
- Chromosomic syndromes and Genome disorders. Uniparental disomy . Uniparental diploidy
- Genetic counselling, genetic tests, prenatal diagnosis. - Parent-of-origin effects, imprinting and genomic imprinting disorders.
Diseases due to expansion of unstable repeat sequences (dynamic mutations). Unstable repeat expansion, premutation and full mutation, Sherman's paradox, anticipation.
-- Hereditary. Mendelian inheritance and atypical inheritance patterns: Mitocondrial inheritance
- Bases of human genetics. Human genome organization, gene order on human chromosomes. Structure of eukaryotic genes. Repetitive DNA. DNA polymorphisms: RFLP, SNP, VNTR, minisatellites, microsatellites. Genetic markers, physical and genetic maps. Linkage Disequilibrium.
- Pedigree construction and analysis.
- Gene and chromosomal mutations, mutation nomenclature. Mutagenesis and DNA repair. Molecular pathology of the gene: biological relevance and effect on the phenotype of mutations, methods for mutation classification as disease-causing. Gain and loss of function mutations, dominance and recessiveness. Genotype-phenotype correlation.
- Genetic variation in individuals and populations. Mutation and polymorphism. The Hardy-Weinberg law, allele and genotype frequency calculation. Inbreedeng and relatedness.
- Mendelian disease gene and mutation identification. Positional and functional cloning. Linkage analysis, human gene mapping, sequencing. Identification of disease causing mutations. Direct and indirect mutation analysis.
- Genetic testing. Diagnostic, presymptomatic, susceptibility, heterozygote identification, population genetic screening, neonatal screening.
- Modifier genes and complexity in single-gene disorders.
- The inheritance of multifactorial traits. Genetics of common disorders with complex inheritance, genetic and environmental factors, qualitative and quantitative traits, genetic predisposition to common diseases. General aspects od the identification of genetic factors in complex diseases. Segregation analysis: Mapping of complex traits, Familial and twin studies.
-Parametric and Non parametric Linkage. Linkage disequilibrium. Linkage and association analyses. Candidate gene studies, genome wide association studies (GWAS).
- Pharmacogenetics and precision medicine. Individual variation of drug response. Genes and polymorphisms of drug metabolism and mechanism of drug action. Molecular diagnostics of pharmacogenetic traits.
- Cancer genetics.
- Genome scan. Study design, quality control of data, imputation, risk assessment, linkage and association.
- Genome sequencing and Genomic, Exomic, and Transcriptomic analysis. Gene counting. Isoforms. Bioinformatics and Genomics.
Bibliography
Didactic methods
The methods adopted for teaching consist of lectures with interaction with students aimed at transmitting the knowledge required by the program on the relevant topics, with in-depth lessons aimed at achieving the objectives of the course.
Learning assessment procedures
The exam consists of an oral test based on all the course contents
Evaluation criteria
The task of the exam consists in verifying the comprehension of course contents and the ability to properly describe their arguments with appropriate scientific language.
Examination methods are the same for students who attended and for those who did not attend the course.
Exam language
Inglese
