Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Type D and Type F activities
Queste informazioni sono destinate esclusivamente agli studenti e alle studentesse già iscritti a questo corso. Se sei un nuovo studente interessato all'immatricolazione, trovi le informazioni sul percorso di studi alla pagina del corso:
Laurea magistrale in Molecular and Medical Biotechnology - Immatricolazione dal 2025/2026.Modules not yet included
Clinical proteomics (2018/2019)
Teaching code
4S003688
Teacher
Coordinator
Credits
6
Language
English
Scientific Disciplinary Sector (SSD)
CHIM/01 - ANALYTICAL CHEMISTRY
Period
I semestre dal Oct 1, 2018 al Jan 31, 2019.
Learning outcomes
The aim of clinical proteomics is actually to find molecular signatures, to describe affected pathways and possibly identify candidate biomarkers that can help in the diagnosis, prognosis and prediction of therapeutic outcomes and elucidate pathogenic mechanisms.
Upon completing the course, students will have the knowledge necessary to recognize the strengthens and weakness of the different proteomics methodologies and of their application to current areas of clinical investigation.
Program
• Introduction to clinical proteomics
• Strategies for protein sample preparation
• Gel-based and gel-free clinical proteomics analyses
• Protein Identification by Tandem Mass Spectrometry
• Label-Based MS clinical proteomic approaches
• Advances in clinical proteomics research for biomarkers discovery
• Clinical Proteomics to study Pancreatic Cancer Stem Cells
• Differential profiling of Breast Cancer plasma proteome for biomarkers identification
• Brain tissue proteomic analysis to identify biomarkers of Alzheimer’s Disease
• Evaluation of therapeutic effects of neural stem cells therapy in Parkinson’s disease
• Recent Advances in Cardiovascular disease
• Pharmacoproteomics for elucidating the mechanism of action of anticancer drugs
| Author | Title | Publishing house | Year | ISBN | Notes |
|---|---|---|---|---|---|
| Josip Lovric | Introducing Proteomics: From concepts to sample separation, mass spectrometry and data analysis | Wiley | 2011 | 978-0-470-03524-5 |
Examination Methods
The NON-attending students must contact the coordinator of the course within the first two weeks to be included in the schedule of presentations and to have the scientific paper assigned. It is suggested to attend at least 30% of lessons.
It is mandatory the participation to the entire lesson in which the student exposes the article. It is mandatory (except for non-attending students) also the participation to the lessons in which the colleagues discuss their paper.
The final exam includes the presentation of a scientific paper and a written exam that will cover all the topics of the program.
The final vote is obtained from the following formula: Vote = Vote_exam + max of 2 points per paper presentation.
