Teaching code

4S003663

Teacher

Annarita Mazzariol

Coordinator

Annarita Mazzariol

Credits

6

Language

English

Scientific Disciplinary Sector (SSD)

MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY

Period

Semester 2 dal Mar 4, 2024 al Jun 14, 2024.

Courses Single

Authorized

Lessons timetable Moodle Seminars 0

Learning objectives

At the end of the course the student will be able to understand the biological, environmental, cultural, processing etc that underlie the emergence of new infections and their spread. The molecular aspects of microorganisms that emerge as new agents of infection are also analysed. It is also considered the re-emerging microorganisms that appeared to be public health problems resolved.

Prerequisites and basic notions

no prerequisites

Program

Introduction to the general concepts leading to the emergence of new microorganisms as agents of infection. Multi-drug resistance microorganisms as a major emerging public health problem. Mechanism of action of antibiotics. Antibiotic resistance mechanisms. Main multiresistant microorganisms. Methods for rapid detection of antibiotic resistance. New strategies for contrasting antibiotic resistance: phages and phage therapy. Mechanisms of bacterial resistance to phages. General characteristics, virulence factors, molecular mechanisms, clinical manifestations of bacteria and their emerging infections: Enterobacteria and Escherichia coli O157-H7; Cholera and Vibrio cholerae O139; Helicobacter; Campylobacter; Clostridium difficile; Listeria monocytogenes Legionella; Borrelia and Lyme disease Mycobacteria and tuberculosis General characteristics, virulence factors, molecular mechanisms, clinical manifestations of viruses and their emerging infections: Influenza viruses and avian influenza Ebola viruses and haemorrhagic fever viruses, encephalitis viruses: zika, chikungunia, West Nile viruses etc, Hepatitis B and C viruses, Retroviruses and HIV, Coronavirus: SARS-CoV and MERS-CoV. Monkeypox General characteristics, virulence factors, molecular mechanisms, clinical manifestations of parasites and their emerging infections: malaria and Plasmodium Knowlesi, Prions and prion diseases. Microorganisms considered potential bioterrorist agents

Bibliography

Didactic methods

The lessons will be held in presence with the use of slides that allow the student to follow the lesson. The slides will show the bibliographic references of the articles or reviews from which images or diagrams are taken which allow to understand the mechanisms underlying the phenomena described and allow the student to further study.

Learning assessment procedures

The exam will take place in written mode. The student is required to answer 3 open questions that touch on the topics covered in class. The questions are of a general nature and therefore concern a single topic or they may require consideration of an aspect that concerns several topics.

Evaluation criteria

The student's ability to respond comprehensively and organically to the questions will be evaluated. The completeness of the answer takes into account all the salient aspects of the topic: characteristics of the microorganism, the pathogenesis and the molecular aspects for which it is pathogenic, the reason why it is considered emerging and which factors have a decisive role, etc.

Criteria for the composition of the final grade

The final vote is expressed in thirtieths. Each of the three questions is evaluated in tenths and the sum of the scores obtained in the individual questions constitutes the final score

Exam language

A scelta dello studente: italiano o inglese