Studying at the University of Verona
Study Plan
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea magistrale a ciclo unico in Medicina e chirurgia - Enrollment from 2025/2026The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.
1° Year
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2° Year activated in the A.Y. 2021/2022
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3° Year activated in the A.Y. 2022/2023
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4° Year activated in the A.Y. 2023/2024
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5° Year activated in the A.Y. 2024/2025
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6° Year It will be activated in the A.Y. 2025/2026
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Legend | Type of training activity (TTA)
TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.
Molecular mechanisms of sensory transduction diseases (Corso Elettivo) (2021/2022)
Teaching code
4S009435
Teacher
Coordinator
Credits
1
Language
Italian
Scientific Disciplinary Sector (SSD)
BIO/10 - BIOCHEMISTRY
Period
2° semestre dal Feb 21, 2022 al May 31, 2022.
Learning outcomes
The course aims to provide a molecular perspective on the alteration of basic biochemical and biophysical mechanisms in hereditary sensory pathologies. The phototransduction cascade underlying the triggering of the visual process and the molecular basis of hereditary retinal degenerations will be presented in detail as a paradigmatic example of sensory disease. The most innovative therapeutic approaches for the treatment of rare sensory diseases will also be mentioned.
Program
- Receptors and signal transduction in sensory systems. From stimulus to electrical response.
- The phototransduction cascade in cones and rods as a paradigmatic GPCR-mediated cascade. Genetic diseases of the retina: retinitis pigmentosa, cone and cone-rod dystrophies. The retinoid metabolism and its alteration in hereditary visual diseases.
- Signal transduction in cochlear hair cells and hearing. Genetic alterations of mechanotransduction mechanisms. Hereditary deafness and non-syndromic genetic hearing loss. Usher's syndrome: deafness associated with retinitis pigmentosa.
- Biochemistry of taste and olfaction. Molecular analogies with the visual cascade. Introduction to the genetic alterations of taste and smell. Olfactory sensitivity, hyperosmia and anosmia.
- Innovative therapeutic approaches: gene therapy, liposomes and nanovesicles as transporters of therapeutic molecules, genome editing based on CRISPR/Cas tools.
Bibliography
Examination Methods
Based on attendance. Presence is compulsory for at least 4 of 5 lectures.
Dates:*
4 - 6 - 8 - 11 -13 April, 2022 3 p.m. - 5 p.m.
Room:*
Aula Suzuki, Section of Biological Chemistry, c/o Istituti Biologici
* To be confirmed two weeks before the lectures
The course will take place exclusively in presence.
Recommended year(s)
2-3-4, but also indicated for 5-6
Further information will be provided via the course's Moodle page. Interested students are advised to register as soon as possible and no later than the deadline.
