Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Study Plan
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea in Biotecnologie - Enrollment from 2025/2026The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.
1° Year
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2° Year activated in the A.Y. 2019/2020
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3° Year activated in the A.Y. 2020/2021
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Un insegnamento a scelta1 module to be chosen among the following| Modules | Credits | TAF | SSD |
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Un insegnamento a scelta1 module to be chosen among the followingLegend | Type of training activity (TTA)
TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.
Molecular biology (2019/2020)
Teaching code
4S00800
Credits
12
Language
Italian
Scientific Disciplinary Sector (SSD)
BIO/11 - MOLECULAR BIOLOGY
The teaching is organized as follows:
teoria
laboratorio [1° turno]
laboratorio [2° turno]
Learning outcomes
The aim of this course is to give the students the basic knowledge of the molecular mechanisms concerning transmission, variation and expression of the genetic information.
At the end of the course the students will be able to recognize the major molecular mechanisms of life in prokaryotic and eukaryotic cells.
Program
THEORY
DNA AND CHROMSOMES
The structure and function of DNA
Chromosomal DNA and its packaging in the chromatin fiber
Chromatin structure and function
The global structure of chromosomes
DNA REPLICATION, REPAIR AND RECOMBINATION
DNA replication mechanisms
The initiation and completion of DNA replication in chromosomes
DNA repair
Homologous recombination
Transposition
HOW CELLS READ THE GENOME: FROM DNA TO PROTEIN
From DNA to RNA
From RNA to protein
Protein folding, degradation and the ubiquitin-proteasome system
CONTROL OF GENE EXPRESSION
Control of transcription by sequence specific DNA-binding proteins
Transcription regulators
Molecular genetic mechanisms that create and maintain specialized cell types
Mechanisms reinforcing cell memory in plants and animals
Post-transcriptional controls
Regulation of gene expression by non-coding RNAs
ANALYZING CELLS AND MOLECULES
Isolating cells and growing them in culture
Analyzing and manipulating DNA
Studying gene expression and function
CELL SIGNALING
Principles of cell signaling
Signaling through G-protein-coupled receptors
Signaling through enzyme-coupled receptors
Alternative signalling routes in gene regulation
THE CELL CYCLE
Overview of the cell cycle
The cell cycle control system
S-phase
Mitosis
Cytokinesis
Meiosis
Control of cell division and cell growth
CANCER
Cancer as a microevolutionary process
Cancer-critical genes: oncogenes and tumor suppressors
Cancer therapy
DISCUSSION OF TOPICS CHOSEN FROM THE LITERATURE ON MOLECULAR BIOLOGY
PRACTICAL (video tutorials):
Restriction enzyme digestion
DNA gel electrophoresis
DNA purification from agarose gel
DNA ligation
Bacterial transformation (heat shock method)
Bacterial transformation (electroporation method)
Plasmid purification
Polymerase chain reaction
Immunoprecipitation, co-immunoprecipitation and pull-down assays
SDS-PAGE
Western blotting
Genetic screens
Genetic engineering of model organisms
Expression profiling with microarrays
RNA-seq
Chromatin immunoprecipitation (ChIP)
Bibliography
| Activity | Author | Title | Publishing house | Year | ISBN | Notes |
|---|---|---|---|---|---|---|
| teoria | Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick | Lewin's Genes XII (Edizione 12) | Jones & Bartlett Pub | 2017 | 1284104494 | |
| teoria | Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff | Molecular Biology of the Cell (Edizione 7) | Garland Science | 2017 | 0815344643 | |
| teoria | Nancy Craig, Rachel Green, Carol Greider, Gisela Storz, Cynthia Wolberger, Orna Cohen-Fix | Molecular Biology: Principles of Genome Function (Edizione 2) | OUP Oxford | 2014 | 0199658579 | |
| teoria | Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin | Molecular Cell Biology (Edizione 8) | Macmillan | 2016 | 9781464187445 | |
| teoria | Erik Pierre | Molecular Cloning (Edizione 1) | Ml Books International | 2015 | 1632394685 | |
| teoria | Michael R. Green e Joseph Sambrook | Molecular Cloning: A Laboratory Manual, Fourth Edition (Edizione 4) | CSHL Press | 2012 | 978-1-936113-42-2 | |
| teoria | Geoffrey M. Cooper, Robert E. Hausman | The cell: a molecular approach (Edizione 6) | Sinauer Associates, Inc | 2013 | 978-1-60535-155-1 |
Examination Methods
Oral examination. The final exam consists of three questions concerning any of the topics treated during the course. It is passed if all answers are positive.
Teaching materials e documents
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Articoli e gruppi
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Ballas et al
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Carrano et al
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Cepeda et al
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Choi et al
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Duan2 et al
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Duan et al
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Jin et al
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Koo et al
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Lamers et al
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Mamely et al
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Michel et al
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Mohamed et al
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Raducu et al
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Strohmaier et al and Koepp et al
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Zhang et al
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