Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Study Plan
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea magistrale in Molecular and Medical Biotechnology - Enrollment from 2025/2026The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.
1° Year
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Two courses among the followingThree courses among the followingOne course among the followingOne course among the following2° Year activated in the A.Y. 2023/2024
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| Modules | Credits | TAF | SSD |
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Two courses among the followingThree courses among the followingOne course among the followingOne course among the following| Modules | Credits | TAF | SSD |
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| Modules | Credits | TAF | SSD |
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2 courses among the following ("BIOTECHNOLOGY IN NEUROSCIENCE" 1ST YEAR; "CLINICAL PROTEOMICS" 1ST and2ND YEAR; the other courses 2nd year only)Legend | Type of training activity (TTA)
TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.
Farming molecolare (2023/2024)
Teaching code
4S003677
Teacher
Coordinator
Credits
6
Language
English
Scientific Disciplinary Sector (SSD)
BIO/15 - PHARMACEUTICAL BIOLOGY
Period
Semester 1 dal Oct 2, 2023 al Jan 26, 2024.
Courses Single
Authorized
Learning objectives
The course aims to give the students notions of the use of recombinant systems for the production of biopharmaceuticals. In particular, the course will be focused on the biomolecular techniques used for the expression of recombinant proteins in prokaryotic and eukaryotic systems and the downstream processing and purification for their large-scale production. The different platforms used for the recombinant expression will be studied and compared. The different US and EU normative procedures for biopharmaceutical commercialization will be evaluated and compared. Specific examples of biopharmaceutical produced in recombinant systems and their therapeutic applications like for vaccines and antibodies will be discussed and studied.
Prerequisites and basic notions
Basic knowledge in molecular biology, biochemistry and immunology
Program
General introduction to the concept of Molecular Farming Definition of the drug and biopharmaceutical concept Approval path of a biopharmaceutical Clinical trials and the regulatory path for the approval of a drug Platforms for the expression of recombinant proteins: bacteria, filamentous fungi, yeasts, plants, mammalian cells, insect cells and transgenic animals. Characteristics, transformation methods, scaling-up methods. The main categories of biopharmaceuticals: vaccines, hormones, antibodies, enzymes. Passive immunization Use of antibodies in chronic diseases and for cancer Heterologous production of antibodies Active immunization Main categories of vaccines and production methods Post-translational modifications and glyco-engineering processes of production platforms. Techno-economic analysis for the production of biopharmaceuticals and proteins of industrial interest.
Didactic methods
The course will be delivered in person.
Learning assessment procedures
Oral test, written test (group work) regarding the techno-economic analysis for the treatment of a target disease with biopharmaceuticals and a written essay regarding the production of a specific bio-pharmaceutical (optional).
Evaluation criteria
the student will be tested for his knowledge of the topics covered in the course and for the ability to adapt his/her knowledge to a specific example for the production of a biopharmaceutical both in the techno-economic and production-related fields
Criteria for the composition of the final grade
The final score will derive from the sum of the score relating to the oral exam (26/26), the optional written exam (2/2) and the techno-economic analysis (2/2).
Exam language
English/italian
