Studying at the University of Verona
Here you can find information on the organisational aspects of the Programme, lecture timetables, learning activities and useful contact details for your time at the University, from enrolment to graduation.
Study Plan
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea magistrale in Molecular and Medical Biotechnology - Enrollment from 2025/2026The Study Plan includes all modules, teaching and learning activities that each student will need to undertake during their time at the University.
Please select your Study Plan based on your enrollment year.
1° Year
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Two courses among the followingThree courses among the followingOne course among the followingOne course among the following2° Year activated in the A.Y. 2023/2024
| Modules | Credits | TAF | SSD |
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| Modules | Credits | TAF | SSD |
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Two courses among the followingThree courses among the followingOne course among the followingOne course among the following| Modules | Credits | TAF | SSD |
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| Modules | Credits | TAF | SSD |
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2 courses among the following ("BIOTECHNOLOGY IN NEUROSCIENCE" 1ST YEAR; "CLINICAL PROTEOMICS" 1ST and2ND YEAR; the other courses 2nd year only)Legend | Type of training activity (TTA)
TAF (Type of Educational Activity) All courses and activities are classified into different types of educational activities, indicated by a letter.
Enzymology in medical biotechnology (2022/2023)
Teaching code
4S009682
Credits
6
Language
English
Scientific Disciplinary Sector (SSD)
BIO/10 - BIOCHEMISTRY
The teaching is organized as follows:
Teoria
Laboratorio [1° turno]
Laboratorio [2° turno]
Laboratorio [3° turno]
Learning objectives
The course introduces students to enzymology and the application of enzymes in medical biotechnology and medicine. The students will acquire advanced knowledge on enzymes mechanisms and regulation, technology of enzyme production, new biotechnological strategies in engineering of enzymes aimed to their improved use in the medical and pharmaceutical fields. The main part of the course will be focused on selected applications of enzymes in biomedicine, diagnostics and therapy.
Prerequisites and basic notions
The student should be familiar with the fundamental concepts of biochemistry addressed during an undergraduate biochemistry course
Program
Theory
• Introduction to enzymes and enzyme kinetics
• Production of recombinant enzymes/proteins
• Protein engineering: directed and rationale evolution for production of new enzymes
• Enzyme therapy in metabolic disorders:
1. Lysosomal storage diseases
2. Disorders of amino acid metabolism
3. Disorders of nucleotide metabolism
• Enzymes in cancer therapy
• Fibrinolytic enzymes for thrombolytic therapy
• Diagnostic enzymes
Laboratory
Session1: purification of recombinant wild type cystathionine beta synthase and its pathogenic variants via affinity chromatography. Analysis of the affinity purified enzyme samples by SDS-PAGE.
Session2: characterization of wild type and pathogenic mutants using kinetic and spectrophotometric methods
Didactic methods
Topics are covered by in-class lectures and laboratory training. Students are expected to attend all lectures. Laboratory attendance is mandatory.
Learning assessment procedures
The topics covered will be evaluated in a single exam. The exam consists of a written test (multiple-choice questions and open-ended questions) which aims to assess the level of knowledge of the topics covered during the course.
Evaluation criteria
To pass the exam, the student must demonstrate that they have fully achieved the set learning objectives.
The completeness and accuracy of the acquired knowledge, as well as the ability to present and demonstrate critical thinking, will be evaluated. The examination format is the same for both attending and non-attending students
Criteria for the composition of the final grade
The evaluation of the exam is expressed out of thirty, the minimum mark for passing the exam is 18/30 and the maximum mark is 30/30, to which "honors" can be added (30 cum laude)
Exam language
english
