Teaching code

4S01154

Credits

10

Coordinator

Mario Rosario Buffelli

Language

Italian

Location

VERONA

Scientific Disciplinary Sector (SSD)

BIO/09 - PHYSIOLOGY

Courses Single

Not Authorized

Moodle Seminars 0

The teaching is organized as follows:

Learning objectives

To understand the physico-chemical mechanisms of basic cellular processes: resting membrane polarization, action potential, synaptic communication, muscular contraction, stimuli transduction. To know the function of the cardiovascular and respiratory systems, their regulation mechanisms and coordination in specific tasks like the homeostasis of the internal environment, the regulation of cardiac output, arterial pressure, respiration and acid-base balance, muscular exercise.

Prerequisites and basic notions

What is physiology? Physiology seeks to understand how organs and systems integrate and interact with the goal of maintaining the homeostasis of our body at rest and in response to stress such as environmental conditions, exercise and even disease. Physiology is a quantitative science as it seeks to explain the functioning of the human body on the basis of universal chemical-physical laws. As such, graphical analysis and dimensional analysis are routinely used in physiology to describe the relationships between the variables involved. The ultimate goal of physiology is to describe the integrated dynamic functions between related organs and systems using predictive models. Physiology completes and integrates the knowledge acquired by studying anatomy, biochemistry, physics and chemistry. In order to understand the Physiology course, thy student must assimilate the basic notions of Chemistry, Physics, Biochemistry and Mathematics. In particular: • Chemistry: the concept of pH, molarity, colligative properties of solutions, osmolarity and pressure osmotic, diffusion. • Biochemistry: concepts of enthalpy, free energy entropy; biological macromolecules, their classification and function, the main metabolic pathways, enzymatic kinetics and mitochondrial enzymes, oxidative phosphorylation • Physics: gas physics, electrophysics, surface tension, Laplace's law, basic notions of mechanics, statics and dynamics of fluids, laws of thermodynamics. • Biology: biophysical characteristics of the cell membrane; structure of the cell and cellular organelles; the genetic code; transcription and translation; protein synthesis; membrane receptors; intracellular signals and second messengers (G protein, cyclic AMP, calcium etc etc.); cellular regeneration mechanisms. • Mathematics: concept of logarithm, concepts of function and Cartesian axes, linear, power, exponential functions; methods of manipulating logarithms, concepts of derivative and integral; unit of measurement of the international system.
Preparatory exams: Human Anatomy II, Chemistry and Biological Chemistry;
Physiology I and Biophysics is preparatory to General Pathology and Clinical Pathophysiology

Program

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UL: Esercitazioni di Fisiologia I
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1) Review of scientific papers and questinnaires
2) Instrumental demonstration of cardiopulmonary and neurophysiological phenomena.
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UL: Lezioni di Fisiologia I
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To understand the physico-chemical mechanisms of basic cellular processes: resting membrane polarization, action potential, synaptic communication, muscular contraction, stimuli transduction. To know the function of the cardiovascular and respiratory systems, their regulation mechanisms and coordination in specific tasks like the homeostasis of the internal environment, the regulation of cardiac output, arterial pressure, respiration and acid-base balance, muscular exercise.
The program will be integrated with a section in E-learning (proposal of classic and update papers, questionnaires) and one of whorkshop on the main topics.

Bibliography

Didactic methods

UL: Esercitazioni di Fisiologia I
Practical and simulated exercises on general, muscle, cardiovascular (ECG), respiratory, and muscle exercise physiology will be organized in the classroom.

UL: Lezioni di Fisiologia I
Teaching will be delivered through lectures.

Learning assessment procedures

Oral interview. The student will be questioned on each of the two main topics (Physiology of neuron and muscle cells, Cardiorespiratory Physiology), with two or three questions from each of the two examiners. There are no ongoing tests.

Evaluation criteria

The student will be asked to illustrate the main concepts related to the topics detailed in the program also with the aid of graphs and equations in order to highlight the quantitative aspects of physiology. Exposure skills and clarity of exposure will be evaluated, as well as the ability to quantitatively illustrate the mechanisms that regulate the physiological homeostasis of organs and systems. In particular, the student's ability to reason in an integrative way and, therefore, to illustrate the integrated physiological adaptations in response to perturbations will be appreciated.

Criteria for the composition of the final grade

The examiner will propose a mark in 30/30, which will result in a weighted average according to the CFU of the two modules and the mark of 30/30 proposed by the professor of the other module.

Exam language

Italiano

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