Learning objectives

The aim of this course is to cover a few general mechanisms of cell damage, giving information useful to understand the development of molecular pathology towards cell, tissue and organism pathology. The course covers the most important examples of damage to sub-cellular structures, particularly to the plasma membrane, describing in some details examples of alterations of transport, adhesion and signal transduction by membrane receptors. Different type of cell necrosis, factors determining regeneration or repair of injured tissues and molecular and cellular basis of reparative reactions and their pathologic consequences are also illustrated.

Prerequisites and basic notions

Bachelor's Degree

Program

1) Introduction to pathology
2) Cellular pathology
3) Oncology
4) Immunity (introduction)
5) Inflammation and Repair
6) Thrombosis and Shock
7) The immunological damage
Educational objectives: the course will develop topics of General Pathology and Immunology preparatory to the understanding of the basic mechanisms of diseases. These disciplines are located at a critical point, at the crossroads between basic and clinical science. The course therefore aims to establish the essential links between clinical manifestations and fundamental mechanisms, facilitating the understanding of the conceptual bases of the disease.
Contents: The course is organized into 7 main topics. The following will be explained: The general concepts of disease, pathology and etiopathogenesis; basic cellular pathology; elements of tumor formation; innate and adaptive immune responses; acute and chronic inflammation mechanisms; general pathology of shock states, thrombosis and wounds; general pathology of hypersensitivity types I-IV.

Bibliography

Didactic methods

Slides and Videos

Learning assessment procedures

Written exam

Evaluation criteria

Vote - min 18

Criteria for the composition of the final grade

question x 0.6 points

Exam language

English