Teaching code

4S008996

Credits

6

Coordinator

Martina Montagnana

Language

Italian

Courses Single

Not Authorized

Moodle Seminars 0

The teaching is organized as follows:

Learning objectives

The teaching aims to provide the basic knowledge of general and molecular biology and biochemistry, with particular focus on those most useful for understanding and deepening biomedical problems associated with orthopedic techniques, including matters related to regenerative medicine techniques. It also aims to provide the foundations of the experimental method at the basis of modern scientific and technological disciplines, to educate students to scientific rigor and to critical evaluation of experimental data. Upon completion of the course, students will acquire the necessary skills to understand, describe and assess natural, biological phenomena, with particular regard to biomedical issues and will be able to explain the molecular and cellular mechanisms underlying the functioning of the entire organism. They will understand the pathogenetic significance of any alterations of these mechanisms, also demonstrating the ability to present the arguments related to the knowledge acquired in a precise way, with critical evaluation and with appropriate scientific language. MODULE: BIOCHEMISTRY Providing basic knowledge of organic chemistry and biochemistry related to the structure-function relationships of the main classes of biological macromolecules, to the metabolic regulation at molecular level, to the interconnections existing between the different biochemical processes and to the energy transformations connected to them. MODULE: GENERAL, MOLECULAR BIOLOGY AND REGENERATING MEDICINE Part 1 CLINICAL BIOCHEMISTRY: The course aims to provide students with the tools and knowledge for the correct query, execution and interpretation of biochemical tests in different clinical contexts. The course will take into particular consideration the most useful exams in the specific path of the degree course. Part 2 MOLECULAR BIOLOGY AND REGENERATIVE MEDICINE: The aim of the course is to provide a molecular and cellular level description of the main mechanisms involved in the replication, transcription and translation in eukaryotes. The course will provide a detailed description of stem cell biology and bone cell differentiation. The course will also explain the role of stem cells in degenerative diseases. Students will acquire knowledge of the fundamental structures of biological systems in a molecular and cellular perspective and of the mechanisms inherent in the transmission, manipulation and expression of the information contained in the eukaryotic genome with particular reference to stem cells. Students will also understand the use of regenerative medicine techniques applied as therapeutic tools in degenerative pathologies. Students will be able to understand the genetic basis of life and the application of molecular tools in degenerative diseases. They will be able to read and understand advanced biology texts and understand the scientific information relating to the application of cellular and molecular therapies in regenerative medicine. MICROBIOLOGY MODULE: acquisition of skills related to microorganisms (prokaryotes, eukaryotes) and viruses, to their interactions with other organisms, the environment and the host, as well as all knowledge related to the main microbiological techniques used to study, isolate and identify them.

Prerequisites and basic notions

Basic knowledge of the chemistry and biology topics covered by the admission test.

Bibliography

Criteria for the composition of the final grade

The final mark is obtained from the average of the marks obtained in the individual modules.