Studying at the University of Verona
Free choice courses
This information is intended exclusively for students already enrolled in this course.If you are a new student interested in enrolling, you can find information about the course of study on the course page:
Laurea magistrale a ciclo unico in Medicina e chirurgia - Enrollment from 2025/2026General Pathology and Clinical Pathophysiology (2018/2019)
The teaching is organized as follows:
FISIOPATOLOGIA CLINICA
Credits
5
Period
Lezioni 1° semestre 2°- 6° anno, Lezioni 2° semestre 1°- 5° anno
Location
VERONA
Academic staff
PATOLOGIA E FISIOPATOLOGIA GENERALE
Credits
14
Period
See the unit page
Location
VERONA
Academic staff
See the unit page
Learning outcomes
The main task of the course is to examine molecular mechanisms responsible for cell and tissue damage and implicated in the host response to cell damage and in repair of tissue injury. In addition, the course addresses pathophysiological mechanisms at the basis of alterations of the host main homeostatic systems, compensation responses induced by these alterations and their potential significance as mechanisms of diseases.
Program
Module: FISIOPATOLOGIA CLINICA
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Detailed program of General Pathology
- Basic concepts in pathology (health and disease, etiology and pathogenesis, omeostasis, functional reserve)
- General classification of causes of diseases
- Alterations of chomosome structure, gene mutations and molecular basis of genetic diseases
- Alterations of membrane transport
- Alterations of inter-cellular communication and membrane receptor function with reference to lipoprotein receptors and their role in the pathogenesis of atherosclerosis and pathology of adhesive interactions in the context of leukocyte recruitment, platelet aggregation, blood coagul ation and thrombosis
- Alterations of signal transduction
- Pathologies due to ethanol and other common chemical compounds
- Mechanisms of reactive oxygen species formation and their role in cell pathology
- Amyloidosis
- Aging
- Necrosis, apoptosis and nettosis
- Isto-cytological properties of tumor cells
- Properties of tumor cell growth and metastatization
- Chemical carcinogenesis
- Molecular basis of tumor cell transformation: DNA damage DNA mechanisms of repair
- Oncogenes and tumor suppressor genes
- Vascular alterations in acute inflammation
- Mediators of inflammation
- Leukocyte adhesion to the vascular wall, transmigration and movement
- Mechanisms of innate immunity: phagocytosis, cytokine secretion, activation
- Chronic inflammation
- Tissue repair and fibrosis
- Quantitative and qualitative alterations of leukocyte functions
- Synopsis of blood cell pathology
Bibliography
| Author | Title | Publishing house | Year | ISBN | Notes |
|---|---|---|---|---|---|
| Pontieri-Russo-Frati | Patologia Generale e Fisiopatologia Generale (Edizione 5) | Piccin | 2015 | ||
| Kathryn L. McCance, Sue E. Huether | Fisiopatologia ed elementi di patologia generale (Edizione 7) | Edra | 2016 | 978-88-214-4143-1 | |
| Dennis Kasper, Anthony S. Fauci | Harrison - Principi di Medicina Interna | McGraw-Hill | 2016 | ||
| Albi, E., Amberi-Impiombato, F.S., Curcio F., Moncharmont, B., Palese, A. | Le basi cellulari e molecolari delle malattie (Edizione 2019) | Sorbona Idelson Gnocchi | 2018 | ISBN 978-88-7947-671-3 | |
| G. M. Pontieri,L. Frati,M.A. RUSSO | Patologia Generale e Fisiopatologia Generale Tomo 2 (Edizione 5) | PICCIN-NUOVA LIBRARIA | 2015 | ||
| Abul K. Abbas, J. C. Aster, Vinay Kumar | Robbins. Fondamenti di patologia e di fisiopatologia (Edizione 9) | Edra | 2013 |
Examination Methods
Module: FISIOPATOLOGIA CLINICA
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Module: PATOLOGIA E FISIOPATOLOGIA GENERALE
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