Teacher

Alessandra Ruggiero

Referent

Alessandra Ruggiero

Credits

5

Language

English

Class attendance

Free Choice

Location

VERONA

Moodle Seminars 0

Learning objectives

Multiomics is a new approach where the data sets of different OMIC groups are combined during analysis. The different OMIC strategies employed during multiomics are genome, proteome, transcriptome, epigenome, and microbiome. This course aims to describe the different OMIC approach from bench-to-bench side. Each lesson is organized to have a theoretical part on the molecular biological approach and then the second half of the lesson will include an overview of the latest and more relevant papers that used that specific approach. The last lesson will be specifically on the data integration, with a brief explanation of the bioinformatic tools available for analysis of OMICS databases and their application in most recent-high impact publications.

Prerequisites and basic notions

molecular biology

Program

1
Recombinant DNA Technology
2
Nucleic Acid quantification: from bench-to-bench side
3
An introduction to ‘Multi-OMICs Age’
4
Single cell analysis of cluster cells analysis?
5
Advanced Multiparameter Flow Cytometry
6
DNA sequencing & Methylome
7
Methylome vs transcriptome: weaking up the sleeping beauty
8
Transcript (protein)ome: when it all ends…or begins?
9
Proteomics & Metabolomics: an eye on into cell physiology
10
Microbiome & Virome: the good, the bad and..
11
The ugly: dissecting pharmacoresistance
12
Data Integration: using the bricks to build ‘the house”

Bibliography

Didactic methods

in presence
live zoom
recorded lessons available

Learning assessment procedures

none

Assessment

none

Criteria for the composition of the final grade

none

Scheduled Lessons