Training and Research
PhD Programme Courses/classes
This page shows the PhD course's training activities for the academic year 2024/2025. Further activities will be added during the year. Please check regularly for updates!
Gut Microbiota: From the Forgotten Organ to a Potential Key Player in Pathology
Credits: 0.5
Language: inglese
Teacher: Elena Zenaro
Cancer immunotherapy in cancer
Credits: 0.5
Language: Inglese
Teacher: Francesco De Sanctis
Genome regulation by long non coding RNAs
Credits: 0.5
Language: English
Teacher: Barbara Mariotti
Endothelial cells
Credits: 0.5
Language: Italian
Teacher: Carlo Laudanna
Kidney cancers: anatomo clinical approaches
Credits: 0.5
Language: Inglese
Teacher: Guido Martignoni
Training the innate immunity
Credits: 0.5
Language: Italian
Teacher: Flavia Bazzoni
Dalla Patologia alla Genomica e ritorno
Credits: 0.5
Language: Inglese
Teacher: Andrea Mafficini
Lung cancer as the paradigm of precision medicine
Credits: 0.5
Language: English
Teacher: Sara Pilotto
Approaches to study intra-tumor heterogeneity
Credits: 0.5
Language: Inglese
Teacher: Vincenzo Corbo
Radiomics in Oncology
Credits: 0.5
Language: inglese
Teacher: Riccardo De Robertis Lombardi
Advanced microscopy for the study of tissue pathology and cellular dysfunction
Credits: 0.5
Language: Italian
Teacher: Enrica Caterina Pietronigro
Tissue resident memory CD8 T cells
Credits: 0.5
Language: English
Teacher: Eleonora Terrabuio
Citometria a flusso: principi, pratica e tecniche avanzate
Credits: 0.5
Language: English
Teacher: Andrea Mafficini
Precision Functional Genomics in Cancer
Credits: 0.5
Language: Inglese
Teacher: Vincenzo Corbo
Myeloid cells induced by cancer
Credits: 0.5
Language: INGLESE
Teacher: Stefano Ugel
Precision Medicine in Pancreatic Cancer
Credits: 0.5
Language: English
Teacher: Claudio Luchini
slan+-monocytes in health and disease
Credits: 0.5
Language: English
Teacher: Marco Antonio Cassatella
The effects and mechanisms of a lifestyle-based approach on cancer-related outcomes
Credits: 0.5
Language: English
Teacher: Sara Pilotto
Ruolo dei neutrofili nella neurodegenerazione
Credits: 0.5
Language: inglese
Teacher: Gabriela Constantin
Immunità meningeale durante condizioni fisiologiche e patologiche
Credits: 1
Language: Italian
Teacher: Gabriela Constantin
Le risposte antivirali del sistema immunitario
Credits: 0.5
Language: English
Teacher: Nicola Tamassia
Neutrophil heterogeneity in health and diseases
Credits: 0.5
Language: Italian
Teacher: Patrizia Scapini
Mechanisms of cancer cells adaptation to microenvironmental challenges
Credits: 0.8
Language: Inglese
Teacher: Vincenzo Corbo
T cell activation: the role of CD1
Credits: 0.5
Language: Inglese
Teacher: Barbara Rossi
Biomarcatori per l'implementazione dell'oncologia di precisione
Credits: 0.5
Language: English
Teacher: Michele Milella
Progettazione e conduzione di studi clinici di fase 1 per lo sviluppo di nuove terapie sperimentali contro il cancro
Credits: 0.5
Language: English
Teacher: Davide Melisi
Fluorescent in situ hybridization analysis (FISH) on cancer
Credits: 0.5
Language: italiano
Teacher: Matteo Brunelli
Modulazione della resistenza al trattamento nell'adenocarcinoma pancreatico duttale agendo sul microambiente tumorale
Credits: 0.5
Language: English
Teacher: Davide Melisi
Alterazioni molecolari nei gliomi
Credits: 0.5
Language: inglese
Teacher: Valeria Barresi
Applicazione della tecnologia degli organoidi in fibrosi cistica
Credits: 0.5
Language: english
Teacher: Claudio Sorio
Radiomics in Oncology
Credits: 0.5
Language: Italian
Teacher: Riccardo De Robertis Lombardi
Twist and turn on the path of precision oncology in routine clinical practice
Credits: 0.5
Language: English
Teacher: Michele Milella
Mechanisms of cancer cells adaptation to microenvironmental challenges (2024/2025)
Teacher
Referent
Credits
0.75
Language
Inglese
Class attendance
Free Choice
Location
VERONA
Learning objectives
The course is designed to provide students with basic knowledge regarding the influence of microenvironmental components on the evolutionary trajectories of solid tumors.
Prerequisites and basic notions
No specific prerequisites
Program
Regarding microenvironmental constraints, the lesson will focus on the effect of stromal elements depletion (e.g. fibroblasts), nutrient deprivation and pharmacological treatments. Regarding the molecular determinants underlying these adaptive processes, the lesson will focus mainly on genetic factors. In addition to the basic concepts, the methodological (in silico and ex vivo modeling) and technological (bulk and single-cell sequencing) approaches for the study of these processes will be presented to the students. In particular, the teacher will present data generated in the laboratory using tumor organoids following the depletion of "niche factors" from the culture medium in order to mimic the depletion of stromal elements.
Didactic methods
Frontal lesson with slide support. Bibliographic references will be provided
Learning assessment procedures
No exams scheduled
Assessment
No rating
Criteria for the composition of the final grade
No vote expected
Scheduled Lessons
| When | Classroom | Teacher | topics |
|---|---|---|---|
|
Friday 18 July 2025 14:00 - 17:00 Duration: 3:00 AM |
To be defined | Vincenzo Corbo | The course is designed to provide students with basic knowledge regarding the nature and significance (both biological and clinical) of intratumoral heterogeneity. A clear distinction will be made between genetic differences (point mutations, copy number variations) and epigenetic differences (different transcriptional states and/or local or general chromatin accessibility). Subsequently, the main technologies and methodologies for studying genetic heterogeneity (e.g., bulk sequencing, comparative lesion sequencing) will be presented, along with statistical approaches for inferring the clonal structure of cancer and phylogenetic relationships between samples from the same patient (primarily based on "variant allele frequency"). Using specific examples from high-profile recent literature, students will be introduced to the main theories on the temporal evolution of solid tumors that explain intratumoral heterogeneity. Finally, new methodologies such as single-cell DNA sequencing and spatial genomics will be briefly discussed. |
